So, say you have a certain [program](http://www.microsoft.com/mac/products/office2004/office2004.aspx?pid=office2004) who’s [developers](http://www.microsoft.com/mac/macbu/default.aspx?pid=macbu) figure it’s alright to pollute users’ home folders…

What to do?

$ /Developer/Tools/SetFile -a V  \
  ~/Documents/Microsoft\ User\ Data/

There, much better.